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  • Age-Dependent Anti-migraine Effects of Valproic Acid and Topiramate in Rats.

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    Age-Dependent Anti-migraine Effects of Valproic Acid and Topiramate in Rats.

    Front Pharmacol. 2018;9:1095

    Authors: Huang P, Kuo PH, Lee MT, Chiou LC, Fan PC

    Abstract
    Background: Valproic acid (VPA) and topiramate (TPM), initially developed as antiepileptics, are approved for migraine prophylaxis in adults but not children. The differences in their antimigraine mechanism(s) by age Lees meer

    Source:: Pubmed