Manual acupuncture + usual care was found to be more effective than usual care alone for irritable bowel syndrome (IBS). Interestingly, manual acupuncture was found to be most effective component (RR = 1.38 (95% CI, 1.12 to 1.70)) when added to usual care. Results from a recent component network meta-analysis of 25 RCTs including a total of 3041 patients.